Simultaneous Estimation of Hydrochlorothiazide and Losartan Potassium in Bulk Solid Dosage Form by Chemometric Assisted Spectrophotometric Methods
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چکیده
منابع مشابه
Simultaneous spectrophotometric estimation of Hydrochlorothiazide, Atenolol and Losartan potassium in tablet dosage form.
Two simple, accurate and reproducible spectrophotometric methods have been developed for the simultaneous estimation of Hydrochlorothiazide (Hctz), Atenolol (Atn) and Losartan potassium (Los) in combined tablet dosage forms. The first method involves determination using the simultaneous equation method, the sampling wavelengths selected are, 272.5 nm, 224 nm and 250 nm over the concentration ra...
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Two UV-spectrophotometric and one reverse phase high performance liquid chromatography methods have been developed for the simultaneous estimation of amlodipine besilate, losartan potassium and hydrochlorothiazide in tablet dosage form. The first UV spectrophotometric method was a determination using the simultaneous equation method at 236.5, 254 and 271 nm over the concentration range 5-25, 10...
متن کاملA Novel Quantification Method for the Simultaneous Estimation of Losartan Potassium and Hydrochlorothiazide in Bulk and Tablet Dosage Form Using Simultaneous Equation Method
In this present paper, a novel, sensitive, UVSpectrophotometric simultaneous equation method was proposed for the estimation of Losartan Potassium (LOS.P) and Hydrochlorothiazide (HTZ) in bulk and tablet dosage form. Water: Methanol in the ratio of 95:5 v/v was used as a solvent which exhibits maximum absorption at 215nm for LOS.P and 272nm for HTZ. Beers law was obeyed over the linear range fo...
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Objective: The present study was designed with an objective of a simple, fast, precise, selective and accurate RP-HPLC method was developed and validated for the simultaneous determination of Losartan, Hydrochlorothiazide and Amlodipine from bulk and formulations. Methods: Reverse phase high performance liquid chromatography (RP-HPLC) method was developed and validated for rapid analysis of sim...
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Two chemometric methods were developed for the simultaneous determination of telmisartan and hydrochlorothiazide. The chemometric methods applied were principal component regression (PCR) and partial least square (PLS-1). These approaches were successfully applied to quantify the two drugs in the mixture using the information included in the UV absorption spectra of appropriate solutions in the...
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ژورنال
عنوان ژورنال: IOSR Journal of Pharmacy and Biological Sciences
سال: 2017
ISSN: 2319-7676,2278-3008
DOI: 10.9790/3008-1203066065